Take the exit for "Route 109, Dedham" (Exit 16A). Follow Route 109 toward West Roxbury for 3.7 miles to the traffic light at St. Theresa Avenue. (St. Theresa Church will be in front of you on the right) Turn right onto St. Theresa Avenue. Roxbury Latin is near the top of the hill on the right. There is a sign at the school entrance.
From the Mass Pike
Take the exit for "Route 128/Interstate 95" (Exit 14). Take Route 128 South and follow the directions above.
Take the Jamaicaway. At the second rotary, bear right onto Route 1 South. Pass the Faulkner Hospital and bear right at the foot of the hill onto the V.F.W. Parkway (still Route 1 South). Turn left at the Carrigg (Cemetery) Monument display onto LaGrange Street. At the light at the intersection of Centre Street (at Blanchard's), turn right. Turn left at the first traffic light onto St. Theresa Avenue.